For information to occur, 2 or more things need to happen. Similarly, for an experience to be successful, we need a continuous neural stimulation or summation. This only happens when 2 or more neural connections fire over time to create potential action.
In my opinion, an experience can only happen from a continuous summation of stimuli. Otherwise, just one neural stimulus will quickly degrade over time. But, a continuous flow of stimuli (a mathematical summation) will eventually hit a threshold wherein an experience becomes special.
Advertising understands this principle (probably not to a molecular level). With a calculated bombardment of a message, we can start to create an experience—good or bad.
Design, being a vehicle to convey such messages, can really take advantage of summation. By skillfully including components that can induce continuous neural stimulation—creating summation—we can do more than convey messages, but ultimately, create change.